abstract：PURPOSE:To determine the morphological characteristics of the cornea in eyes with posterior corneal vesicles (PCV) determined by in vivo confocal microscopy (IVCM). In addition, to compare the morphological characteristics of the corneas of eyes with PCV to those of eyes with posterior polymorphous corneal dystrophy (P...

journal_title：Japanese journal of ophthalmology

authors： Shiraishi A,Zheng X,Sakane Y,Hara Y,Hayashi Y

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To determine changes of visual-field (VF) global indices after cataract surgery and the factors associated with the effect of cataracts on those indices in primary open-angle glaucoma (POAG) patients. METHODS:A retrospective chart review of 60 POAG patients who had undergone phacoemulsification and intraocular...

journal_title：Japanese journal of ophthalmology

authors： Seol BR,Jeoung JW,Park KH

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:A national survey was conducted in Japan to analyze the clinical characteristics of pellucid marginal corneal degeneration (PMD). METHODS:A questionnaire was sent to all members of the Japan Cornea Society requesting demographic and clinical findings on PMD patients who had been examined between 2008 and 2010....

journal_title：Japanese journal of ophthalmology

authors： Shimazaki J,Maeda N,Hieda O,Ohashi Y,Murakami A,Nishida K,Tsubota K,Japan Pellucid Marginal Corneal Degeneration Study Group.

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Lymphoproliferative disorders (LPDs) can develop in patients treated with methotrexate (MTX) and usually respond well to MTX withdrawal. Mucosa-associated lymphoid tissue (MALT) lymphoma is a relatively rare type of MTX-LPD. The development of MTX-LPD in the orbit has not been previously described. We here repo...

journal_title：Japanese journal of ophthalmology

authors： Kobayashi Y,Kimura K,Fujitsu Y,Shinkawa K,Muta H,Sonoda KH

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To evaluate the effect of preservative-free (PF) tafluprost on diurnal variation of intraocular pressure (IOP) and ocular perfusion pressure (OPP), measured by use of home IOP and blood-pressure (BP) monitoring devices, for primary open angle glaucoma (POAG) patients. METHODS:Twenty-two eyes from 22 patients w...

journal_title：Japanese journal of ophthalmology

authors： Cho SY,Kim YY,Yoo C,Lee TE

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...

journal_title：Japanese journal of ophthalmology

authors： Han JC,Choi DY,Kwun YK,Suh W,Kee C

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To verify, by use of data collected by the Japan Glaucoma Society Survey of Bleb-related Infection (JGSSBI), that bleb morphology changes within 12 months of the development of bleb-related infection. METHODS:JGSSBI data from 57 eyes of 57 patients with primary open-angle glaucoma and normal tension glaucoma w...

journal_title：Japanese journal of ophthalmology

authors： Sawada A,Kuwayama Y,Yamamoto T

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To evaluate the occurrence of hyperemia with, and efficacy of, bimatoprost 0.01 % for patients in Korea previously treated for open-angle glaucoma (OAG; including normal tension glaucoma) or ocular hypertension (OHT). METHODS:In this multicenter, observational study (Asia Pacific Patterns from Early Access of ...

journal_title：Japanese journal of ophthalmology

authors： Kook MS,Simonyi S,Sohn YH,Kim CY,Park KH

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To investigate the predictive factors of polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy (PCV). METHODS:Sixty-nine eyes (69 patients) with treatment-naïve PCV received an initial series of 3-monthly intravitreal ranibizumab injections, followed by as-needed inje...

journal_title：Japanese journal of ophthalmology

authors： Cho HJ,Han SY,Kim HS,Lee TG,Kim JW

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To compare the cytotoxicity of povidone-iodine solution (PVP-I) with that of polyvinyl alcohol-iodine solution (PAI) for ophthalmic use. METHODS:Cells of the human corneal epithelial cell line HCE-T were exposed to various dilutions of PVP-I or PAI, and the cytotoxicity of these two antiseptics was evaluated. ...

journal_title：Japanese journal of ophthalmology

authors： Shibata Y,Tanaka Y,Tomita T,Taogoshi T,Kimura Y,Chikama T,Kihira K

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To investigate mutations of causal genes in two affected male siblings of a Japanese family with suspected Leber congenital amaurosis (LCA) and to characterize the related clinical features. METHODS:After obtaining informed consent, genomic DNA was extracted from peripheral blood of the proband and his family ...

journal_title：Japanese journal of ophthalmology

authors： Suzuki T,Fujimaki T,Yanagawa A,Arai E,Fujiki K,Wada Y,Murakami A

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:We report here a patient with bilateral papillomacular retinoschisis with an enlarged glaucomatous optic nerve head cup and a focal lamina cribrosa defect, the findings of our clinical investigations of this case, and the chosen treatment and outcome. DESIGN:This is an observational case report. METHODS:Clini...

journal_title：Japanese journal of ophthalmology

authors： Yoshitake T,Nakanishi H,Setoguchi Y,Kuroda K,Amemiya K,Taniguchi M,Otani A

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To estimate the melatonin suppression index (MSI), which may reflect the nonvisual photoreception function, through commercially available foldable, clear and yellow-tinted intraocular lenses (IOLs). METHODS:The MSIs for 13 IOL models (6 clear IOLs, 7 yellow-tinted IOLs) with three lens powers were calculated ...

journal_title：Japanese journal of ophthalmology

authors： Sano I,Tanito M,Okuno T,Ishiba Y,Ohira A

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:To establish a rat glaucoma model with chronic intraocular pressure (IOP) elevation induced by microbeads suspended in sodium sulfate-sodium hyaluronate. METHODS:Chronic elevation of IOP was induced unilaterally by injecting polystyrene microbeads, suspended in 4 % sodium sulfate and 3 % sodium hyaluronate, in...

journal_title：Japanese journal of ophthalmology

authors： Matsumoto Y,Kanamori A,Nakamura M,Negi A

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To assess the proportion of glaucomatous eyes based on the association between optic disc (OD) size and its clinical determinants in the resident population of Namil-myon, Central South Korea. METHODS:Of the 1,532 participants in the Namil study, we included 1,410 Koreans (2,734 eyes) with legible fundus photo...

journal_title：Japanese journal of ophthalmology

authors： Kang NH,Jun RM,Choi KR,Namil Study group, Korean Glaucoma Society.

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:To report the reproducibility profile of optic nerve head parameters obtained by computer software-assisted fundus photoplanimetry. METHODS:Fundus photographs obtained during a population-based health survey (Sakurae Study) were planimetrically analyzed using newly developed computer software, CDSketch. The pa...

journal_title：Japanese journal of ophthalmology

authors： Tanito M,Sagara T,Takamatsu M,Kiuchi Y,Nakagawa T,Fujita Y,Ohira A

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To evaluate the capability of optical coherence tomography (OCT), retinal nerve fiber layer (RNFL) thickness, and visual field (VF) measurements in glaucoma progression detection. METHODS:The study examined 62 eyes of 37 glaucoma patients observed over a 3-year period. All eyes underwent at least four serial R...

journal_title：Japanese journal of ophthalmology

authors： Tenkumo K,Hirooka K,Baba T,Nitta E,Sato S,Shiraga F

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To report on isolated central retinal artery occlusion (CRAO) as an initial presentation in two patients with undiagnosed paroxysmal nocturnal hemoglobinuria (PNH). METHODS:CRAO related to the aggravation of PNH was observed in 2 of 98 consecutive PNH patients for 10 years. Ocular and systemic manifestations w...

journal_title：Japanese journal of ophthalmology

authors： Yang HS,Park SH,Choi JR,Kim JG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To explore methods of automated visual field (VF) examination for the assessment of macular function. METHOD:We used a VF examination (AP-7000 automatic perimeter, Kowa, Japan) to examine macular function in 53 eyes from 29 patients with open angle glaucoma. We measured the mean total deviation (c-MD) of 16 po...

journal_title：Japanese journal of ophthalmology

authors： Omodaka K,Kunimatsu-Sanuki S,Morin R,Tsuda S,Yokoyama Y,Takahashi H,Maruyama K,Kunikata H,Nakazawa T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To measure choroidal thickness in healthy pregnant women using enhanced depth imaging optical coherence tomography (EDI-OCT) and compare the measurements with those of healthy non-pregnant women. METHODS:Choroidal thickness was measured at the fovea and at 3 mm superior, inferior, temporal, and nasal to the fo...

journal_title：Japanese journal of ophthalmology

authors： Takahashi J,Kado M,Mizumoto K,Igarashi S,Kojo T

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To compare the detection of localized retinal nerve fiber layer (RNFL) defects by two different spectral domain optical coherence tomography (SD-OCT) devices. METHODS:Eyes of 42 normal control subjects and 48 patients with a localized RNFL defect on red-free fundus photographs were imaged by the Cirrus (Carl Z...

journal_title：Japanese journal of ophthalmology

authors： Kim KE,Ahn SJ,Kim DM

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the usefulness of laser speckle flowgraphy (LSFG) for the differentiation of acute nonarteritic ischemic optic neuropathy (NAION) from anterior optic neuritis (ON). METHODS:To investigate blood flow in the optic disc under normal conditions, NAION, and anterior ON, we c...

journal_title：Japanese journal of ophthalmology

authors： Maekubo T,Chuman H,Nao-I N

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To evaluate dry eye symptoms, tear film function and ocular surface changes in patients with psoriasis. METHODS:The Dry Eye Questionnaire and ophthalmic examination including the Schirmer test, tear break-up time, corneal fluorescein test, meibomian gland obstruction and conjunctival impression cytology were a...

journal_title：Japanese journal of ophthalmology

authors： Her Y,Lim JW,Han SH

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To present and compare the long-term results of Dr. Tamcelik's previously described technique of Tenon advancement and duplication with the conventional Ahmed glaucoma valve (AGV) implantation technique in patients with refractory glaucoma. METHODS:This study was a multicenter, retrospective case series that i...

journal_title：Japanese journal of ophthalmology

authors： Tamcelik N,Ozkok A,Sarıcı AM,Atalay E,Yetik H,Gungor K

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:The purpose of this study was to estimate the optimal size of visual field test for detecting longitudinal changes in retinitis pigmentosa (RP) by dividing the visual field. METHODS:We reviewed the results of 10° static visual field tests in 19 eyes of 19 RP patients. Sixty-eight numeric value points were divi...

journal_title：Japanese journal of ophthalmology

authors： Ogino K,Otani A,Oishi A,Kurimoto M,Sekiya T,Yoshimura N

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To examine using the folds of the retinal pigment epithelium (RPE) to diagnose Vogt-Koyanagi-Harada (VKH) disease. METHODS:Retrospective clinical review of 57 Japanese patients between July 2005 and April 2009. Optical coherence tomography (OCT), fundus photographs and fluorescein angiography (FA) were studi...

journal_title：Japanese journal of ophthalmology

authors： Kato Y,Yamamoto Y,Tabuchi H,Fukushima A

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To measure changes in choroidal thickness (CT), retinal thickness (RT), and axial length (AL) accompanying intraocular pressure (IOP) increase and to investigate the changes in axial eye dimensions induced by IOP increase. METHODS:Thirty-four eyes of 34 patients undergoing a diagnostic provocative test for pri...

journal_title：Japanese journal of ophthalmology

authors： Hata M,Hirose F,Oishi A,Hirami Y,Kurimoto Y

更新日期：2012-11-01 00:00:00

abstract：:For the past 30 years, I have worked as a physician-scientist in both the clinic and laboratory setting at a number of university medical schools. Encountering patients in the clinic for whom treatment was not available led me to the laboratory in an attempt to develop the appropriate treatment for future patients. Th...

journal_title：Japanese journal of ophthalmology

authors： Nishida T

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To investigate the frequency of infraorbital nerve enlargement (IONE) in orbital lymphoproliferative disorders, and to show that IONE can contribute to the clinical diagnosis of IgG4-related orbital diseases (IgG4-ROD). SUBJECTS AND METHODS:71 cases in which orbital lymphoproliferative disorders were diagnosed...

journal_title：Japanese journal of ophthalmology

authors： Ohshima K,Sogabe Y,Sato Y

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To investigate the seasonal variations in myopia progression and axial elongation in Japanese children. METHODS:Ninety-two children who were enrolled in a myopia-control trial and wearing single vision or progressive addition lenses were included in the analyses (mean ± SD age 11.4 ± 1.7 years, mean spherical ...

journal_title：Japanese journal of ophthalmology

authors： Fujiwara M,Hasebe S,Nakanishi R,Tanigawa K,Ohtsuki H

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:Sweet's syndrome (SS) is a skin disorder clinically characterized by fever, neutrophilia, and painful edematous plaques that occasionally causes posterior uveitis. We present two cases of SS with panuveitis resembling Behçet's disease (BD). SUBJECTS:Two patients with panuveitis associated with SS. OBSERVATION...

journal_title：Japanese journal of ophthalmology

authors： Matsumiya W,Kusuhara S,Yamada Y,Azumi A,Negi A

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To report three types of heterozygous mutations in the OPA1 gene in five patients from three families with autosomal dominant optic atrophy (ADOA, MIM#165500). METHODS:DNA was extracted from the leukocytes of the peripheral blood. For mtDNA, mutations were examined at positions 11778, 3460 and 14484. For the O...

journal_title：Japanese journal of ophthalmology

authors： Hamahata T,Fujimaki T,Fujiki K,Miyazaki A,Mizota A,Murakami A

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To verify the current Japanese classification of vision disability in regard to visual acuity. METHODS:A questionnaire was sent to 100 ophthalmology services in Japan. Each service was asked to extract 300 of their outpatient records. From these records, patients who had a sum of corrected visual acuity in bot...

journal_title：Japanese journal of ophthalmology

authors： Nishida T,Ando N,Sado K,Nakadomari S

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:We evaluated central retinal thickness (CRT) in diabetic macular edema (DME) using two different spectral-domain (SD) optical coherence tomography (OCT) instruments: the Cirrus and Spectralis OCTs. METHODS:CRT was measured in 63 eyes of 32 patients with DME using both instruments on the same day. RESULTS:CRT ...

journal_title：Japanese journal of ophthalmology

authors： Suzuma K,Yamada Y,Liu M,Tsuiki E,Fujikawa A,Kitaoka T

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To describe the characteristics and clinical course of patients with active posterior syphilitic uveitis evaluated between 1991 and 2009. METHODS:Retrospective chart review. RESULTS:Thirteen patients with active posterior syphilitic uveitis were identified at a single institution. All were men, and all with a...

journal_title：Japanese journal of ophthalmology

authors： Li SY,Birnbaum AD,Tessler HH,Goldstein DA

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:We evaluated the use of immunological biomarkers in transconjunctival immunotherapy by using cholera toxin B for treating experimental allergic conjunctivitis in a mouse model. METHODS:Balb/c mice were sensitized using intraperitoneal injections of ovalbumin (OVA) and were then divided into two groups. The fir...

journal_title：Japanese journal of ophthalmology

authors： Oikawa A,Shoji J,Inada N,Sawa M

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:The aqueous humor (AH) contains numerous immunosuppressive molecules that contribute to the ocular immune privilege. Here, we mimic an inflammatory environment to analyze the inhibitory effects of the AH on lipopolysaccharide (LPS)-induced maturation of dendritic cells (DC). METHODS:Different concentrations of...

journal_title：Japanese journal of ophthalmology

authors： Wang HF,Liu JL,Jiang XL,Lu JM,Li XL,Song XJ

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:We investigated by in vivo confocal microscopy alterations in the subepithelial nerve plexus in different types of herpes simplex keratitis (HSK). METHODS:Seventeen patients (seven women and ten men, mean age 63.9 years) with a history of HSK were classified into three groups according to the classification of...

journal_title：Japanese journal of ophthalmology

authors： Nagasato D,Araki-Sasaki K,Kojima T,Ideta R,Dogru M

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:We previously reported that human conjunctival epithelial cells expressed functioning interleukin-4 receptor α (IL-4Rα). In this study, we investigated whether human corneal epithelial cells also express functioning IL-4Rα. METHODS:The presence of IL-4Rα mRNA and protein in human corneal epithelium was examine...

journal_title：Japanese journal of ophthalmology

authors： Ueta M,Sotozono C,Kinoshita S

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:To verify the advantages of trabeculotomy combined with phacoemulsification, intraocular lens implantation and sinusotomy (PTOS) in eyes with exfoliation glaucoma (XFG) and a coexisting cataract. PATIENTS AND METHODS:Sixty-six eyes of 62 Japanese XFG patients that received either PTOS, phacotrabeculectomy (PTE...

journal_title：Japanese journal of ophthalmology

authors： Fukuchi T,Ueda J,Nakatsue T,Suda K,Hara H,Abe H

更新日期：2011-05-01 00:00:00